https://graduate.ouhsc.edu/Postdoctoral-Fellows Parent Page: Postdoctoral Fellows id: 26953 Active Page: Available Positionsid:27401

Available Positions

Postdoctoral Position in Regenerative Bone Biology

A postdoctoral position is available at the University of Oklahoma Health Sciences Center in Dr. Mary Beth Humphrey’s lab to study molecular mechanisms of mesenchymal stem cell regulation and  the role of vagal nerve stimulation in prevent pain and joint destruction in mouse models of osteoarthritis.

Candidate should have a Ph.D. with experience in bone biology, immunology, molecular biology, cell biology, or biochemistry.  Experience with mammalian cell culture, recombinant DNA technology, cellular signaling and mouse models of bone disease are preferred.   Candidate must be able to plan and perform experiments in an independent manner with appropriate supervision, have excellent communication skills and strong interpersonal skills.  Candidate will also be responsible for writing papers, protocols and lab reports associated with this project. Highly motivated individuals who wish to develop careers as independent scientists are encouraged to apply.  Preference will be given to candidates with documented success in research, such as recent first author publications and aspirations for an independent scientific career.  Please provide your CV, letter of interest, and contact information for 3 references, including current employer by email.

Contact via e-mail to marybeth-humphrey@ouhsc.edu.

Posted 9/28/22

Postdoctoral Fellow Position in the Department of Microbiology and Immunology, College of Medicine

A NIH-supported postdoctoral position is available in the Zenewicz laboratory at the University of Oklahoma Health Sciences Center, Department of Microbiology & Immunology, College of Medicine in Oklahoma City, OK.  We are seeking a postdoctoral fellow to conduct research on the role of the cytokine interleukin-22 (IL-22) in immune homeostasis and inflammation, with a focus on bacterial infection.  IL-22 is a crucial regulator of tissue responses during inflammation.  The successful candidate will pursue research to determine the mechanisms of IL-22-mediated protection in the gastrointestinal (GI) tract during Clostridioides difficile infection, a mucosal-associated bacterial pathogen that is a leading source of hospital-acquired GI infections.  We are currently focused on understanding the cellular metabolism of T cells and innate lymphocytes.  Our long-term goal is to identify how the immune system may be therapeutically targeted to alleviate initial C. difficile infection or relapses in high-risk patients.  New biologics targeting cytokines have revolutionized management of inflammatory bowel disease and other chronic inflammatory diseases, providing a precedent for their possible use in the treatment of infectious diseases.

Applicants should hold a Ph.D., M.D. or D.V.M. and have a background in immunology and/or microbiology.  Excellent oral and written communication skills, organization skills, and demonstrable publication record in the field of immunology or microbiology are preferred.  Experience with multi-parameter flow cytometry and familiarity with standard immunologic, molecular biology, tissue culture techniques, and rodent models of disease is desirable in a candidate.

For more information on our laboratory and recent publications, please see:

https://basicsciences.ouhsc.edu/mi/Faculty-and-Staff/Primary-Faculty/lauren-zenewicz-phd-1

To apply: Applicant should email in a single PDF: a cover letter describing their research interests and short- and long-term goals, a CV and the names and contact information of three references directly to Lauren A. Zenewicz, Ph.D., lauren-zenewicz@ouhsc.edu

 

Posted 9/27/22

Postdoctoral Fellow in the Department of Medicine, Division of Rheumatology, Immunology and Allergy

A position for a post-doctoral fellow is available in the laboratory of Dr. Carol Webb in the Department of Medicine, Division of Rheumatology, Immunology and Allergy at the University of Oklahoma Health Sciences Center in Oklahoma City. We are seeking a highly motivated person with an outstanding work ethic. Funded projects seek to determine mechanisms for autoimmune activation in human blood cells and for development of kidney organoid cultures from adult stem cells. Prior experience with tissue culture, flow cytometry and molecular biology would be beneficial. Successful candidates will have strong oral and written communication and organization skills. The environment at OUHSC is diverse and inclusive.

To apply, email a cover letter describing research interests, a CV and names and contact information of three references directly to Dr. Webb at carol-webb@ouhsc.edu.

Posted 9/22/22

Postdoctoral Fellow Position at Hannafon Laboratory

The Hannafon Laboratory at the University of Oklahoma Health Sciences Center is seeking a postdoctoral fellow to study drug development and anti-tumor targeting mechanisms of a novel therapeutic combination in breast cancer. The successful candidate should be a highly ambitious and self-motivated scientist with good organization skills, and excellent written and verbal communication skills.

The research focus of the Hannafon laboratory is to discover and investigate the molecular mechanisms of breast and gynecologic cancer development, progression, therapeutic response, and resistance. We are especially interested in the role of small extracellular vesicles, known as exosomes, in intercellular communication in the tumor microenvironment, and evaluate their use as biomarkers. An additional focus of the laboratory is anti-cancer drug development for improved targeting and therapeutic response in gynecologic and breast cancers.

Interested candidates should send a CV, a brief one-paragraph description of previous research experience, and a list of 3 references to Bethany-hannafon@ouhsc.edu

Requirements

Teamwork: Being a good laboratory member and working collaboratively with others.

Cell culture. Maintain cell cultures and reagents, and cell line inventories. Conduct experiments to analyze the effects of treatments using various assays. 

Animal Testing. Must Perform specialized tests on experimental animals including tumor cell injection, weighing, administration of drugs, maintaining a census, and surgeries in mice models. 

Molecular, Cellular, and Biochemical Analysis. Perform a variety of assays on cell cultures, and human or animal tissues, including DNA/RNA/protein extraction, PCR, growth assays, immunoblotting, and other specific routine assays, as required. 

Data Collection and Maintenance.  Enter, compile and graph data, maintain a laboratory notebook, and file reports. May perform data analysis. 

Equipment Maintenance.  Maintain laboratory space, laboratory supplies, and equipment, assesses lab group needs to order and stock supplies and equipment. 

And as Needed.  Perform various duties as needed to successfully fulfill the function of the position.

Duties

The candidate will be expected to perform research, write manuscripts, and present findings at local and national meetings. The candidate will also assist in writing grant proposals and will be highly encouraged to submit fellowship applications (both intramural and extramural).

Preferred

Previous experience in Animal handling and willingness to work with mice.

Application

Please submit the following documents to Bethany-hannafon@ouhsc.edu

  • CV
  • One paragraph description of previous research experience
  • List of 3 professional references.
 
Remains valid as of 9/5/22

Postdoctoral Fellow Position in the Department of Pharmaceutical Sciences, College of Pharmacy

A postdoctoral position is immediately available in the Yue laboratory in the Department of Pharmaceutical Sciences, College of Pharmacy at the University of Oklahoma Health Sciences Center. The Yue laboratory is seeking a highly motivated postdoctoral fellow to conduct NIH-funded projects on drug transport proteins. The postdoctoral fellow will study the role and regulation of organic anion transport polypeptide (OATP1B1) and OATP1B3 in drug disposition, aiming to mitigate transporter-mediated drug-drug and drug-disease interactions. Drug transport protein-related research has grown exponentially in the past decade driven by the emergence of the Food and Drug Administration (FDA) Critical Path Initiative and subsequent white papers (Nat Rev Drug Discovery, 2010, 9: 215; Clin Pharmacol Ther, 2018, 104:890; Clin Pharmacol Ther, 2022, 112: 461) and the guidance for industry from the US FDA (https://www.fda.gov/media/134582/download). Multi-disciplinary approaches are utilized in the Yue research program. These approaches include 1) sandwich-cultured primary human hepatocytes; 2) gene-knockout models; 3) proteomics; 4) molecular and cell biology approaches, including confocal microscopy; 5) pharmacogenomics studies; and 6) physiologically-based pharmacokinetic (PBPK) modeling and simulation. For more information, visit https://sites.google.com/view/yuelab

Successful candidates should have a Ph.D. in Cell Biology, Molecular Biology, Pharmaceutical Sciences, Pharmacology, Biochemistry, Immunology, or a related field. Preference will be given to applicants with at least one first-author publication in a reputable journal. Required qualifications are Ph.D., M.D., or Ph.D./M.D. Experience in mammalian cell culture, aseptic technique, and standard cell and molecular biology techniques, including DNA/RNA extraction and immunoblot, are required. Experience with real-time RT-PCR is preferred, but not required. Individuals with experience in protein post-translational modifications and epigenetics are particularly encouraged to apply. Competitive candidates are expected to have excellent oral and written communication skills. Review of applications will begin immediately and the position will remain open until filled. To apply, please send the following materials: a cover letter containing a brief summary of the applicant’s current research, research interests, and career goals; curriculum vitae/resume; contact information for three references; and reprints of the applicant’s publications to Dr. Wei Yue, wei-yue@ouhsc.edu.

Posted 9/1/2022

Postdoctoral Fellow Position at Stephenson Cancer Center

A postdoctoral position at the Stephenson Cancer Center, University of Oklahoma Health Sciences Center (OUHSC) in Oklahoma City, Oklahoma, is immediately available to study chronic lymphocytic leukemia (CLL) biology and signaling involving crosstalk of the malignant cells with the CLL tumor microenvironment.

A highly motivated scientist with a fresh PhD is encouraged to apply. Candidates with experience in cancer biology, molecular biology, and animal models (xenograft as well as transgenic) are preferred. The candidate should have first-hand experience in routine laboratory techniques including but not limited to cell culture, western blots, immunoprecipitation, apoptosis assays, confocal microscopy, PCR/qRT-PCR and other related biochemical assays. Experience in flow cytometry will be an added qualification.

To apply, please send a cover letter stating your research interests and experience along with a curriculum vitae and three references to asish-ghosh@ouhsc.edu.

The Stephenson Cancer Center is an NCI-designated cancer center with interacting teams of scientists supported by an array of core facilities and located on a large OUHSC research campus. OUHSC is one of only four comprehensive academic health centers in the nation with seven health professional schools, providing a broad base of expertise for comprehensive clinical and basic science research, interdisciplinary interaction, and career development. Oklahoma City is a large metropolis with western charm, easy local transportation, vibrant downtown, and excellent suburbs.

The University of Oklahoma Health Sciences Center is an Equal Opportunity/Affirmative Action employer that is strongly and actively committed to diversity within its community. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, political beliefs, national origin, age (40 or older), sex (see: Sexual Misconduct, Discrimination policy) sexual orientation, genetic information, gender identity, gender expression, disability, or veteran status.

Posted: 7/6/22

Postdoctoral Fellow in Cardiovascular Drug Development at the College of Pharmacy

A lab in University of Oklahoma Health Sciences Center (OUHSC) has an open position for a postdoctoral fellowship in cardiovascular drug development. Applicants with a strong background in cardiovascular research, including rodent model development, cell culture, advanced biochemical techniques, HPLC, etc. are especially encouraged. The successful candidate will be part of a dynamic lab with synergistic skills and experiences and will be given the opportunity to develop new projects that complement the overall directions of the lab. This is a mentored position where incumbents plan, design and conduct research experiments, manage research projects, prepare reports and papers for publication, presentation and future research. The fellow will actively contribute to grant writing and will be encouraged to write applications for independent fellowships. An ideal candidate will have Ph.D. in a biological science, chemistry, or other relevant area, or M.D., or equivalent. History of work in myocardial infarction and/or stroke mouse models preferred. Publication of at least 2-3 peer-reviewed articles is expected. Experience planning and effectively executing animal projects and maintaining animal colonies, surgical techniques, Western blotting, RT-PCR, Flow cytometry and other advanced molecular techniques. Must have the ability to multitask and work both independently and as a member of an interdisciplinary team with attention to detail.

Benchmark Expectations

  • ·       Conduct scientific research.
  • ·       Manage research projects and maintain documentation.
  • ·       Present scientific information both formally and informally.
  • ·       Prepare papers for publication and contribute to grant writing.
  • ·       Perform lab management responsibilities as assigned.
  • ·       Work collaboratively and collegially as part of the team while developing skills needed as an independent scientist.
  • ·       Have experience and/or exposure to cardiovascular or a closely related field.

To apply, please send your current cv and a list of three references (email and phone number) to vawasthi@ouhsc.edu.

Posted 10/04/2021

Postdoctoral Fellow in Infectious Diseases, Department of Medicine

The incumbent will perform research using microbiological, molecular and cellular techniques as well as collaborating with others to perform neuro-cognitive assessments to neuroinflammation and its effects on cognitive function, particularly in the context of aging. Full job description is here.

Inquiries and Applications: Dr Doug Drevets Douglas-Drevets@ouhsc.edu  with a cc to Wendy Newport, Section Manager. 

Posted 9/10/21 (Remains active as of 9/1/22)

Postdoctoral Fellowship in Molecular Mechanisms of Alzheimer’s Disease and the Biology of Brain Aging

A postdoctoral position is available immediately in the Department of Biochemistry and Molecular Biology and the Center for Geroscience and Healthy Brain Aging at the University of Oklahoma Health Sciences Center.  The applicant will work on mechanisms of pathogenesis of Alzheimer’s disease (AD) and related dementias using rodent models, with a specific focus on the role of mechanisms of aging, pathogenic tau, and cerebrovascular pathways of AD.  For more information please see the laboratory’s website https://www.galvanlab.org.

The successful candidate should hold a Ph.D. in neuroscience, biochemistry, genetics, cellular or molecular biology, physiology, or other related fields and have a record of creativity and strong scientific productivity. Working experience on mouse models, assessment of brain vascular function, optical imaging, primary neuron cell culture, molecular biology and mouse genetics, and a background in neuroscience and brain vascular biology are strongly preferred, but not exclusively required. Please provide a curriculum vitae, a brief summary of research experience and goals, and the names and contact information of three references to Dr. Veronica Galvan (galvanv@uthscsa.edu) or to Dr. William Sonntag (william-sonntag@ouhsc.edu) on behalf of Dr. Veronica Galvan.

Posted: June 23, 2021

Postdoctoral Fellow Research in Anti-cancer Drug development Against Gynecological Cancers

The Benbrook Research Group at the University of Oklahoma Health Sciences Center is recruiting a post-doctoral fellow who is collaborative and interested in researching anti-cancer drug development against Gynecological Cancers. Interested candidates should send a CV, a brief one paragraph description of previous research experience, and a list of 3 references to Doris-Benbrook@ouhsc.eduVishal-Chandra@ouhsc.eduRajani-Rai@ouhsc.edu

Requirements:

Cell culture. Maintain cell cultures and reagents, cell line inventories and conduct experiments to analyze effects of treatments using various assays. Animal Testing. Must Perform specialized tests on experimental animals including tumor cell injection, weighing, administration of drugs, maintaining a census, and surgeries in rat or mice models. Molecular, Cellular and Biochemical Analysis. Perform a variety of assays on cell cultures, and human or animal tissues, including DNA/RNA/protein extraction, PCR, growth assays, immunoblotting, and other specific routine assays, as required. Data Collection and Maintenance.  Enter, compile and graph data, maintain laboratory notebook and file reports. May perform data analysis. Equipment Maintenance.  Maintain laboratory space, laboratory supplies and equipment, assesses lab group needs to order and stock supplies and equipment. And as Needed.  Perform various duties as needed to successfully fulfill the function of the position.

Duties:

Candidate will be expected to perform research, write manuscripts, and present findings at local and national meetings. Candidate will also assist in writing grant proposals and will be highly encouraged to submit fellowship applications (both intramural and extramural).

Preferred:

  • Previous experience in Animal handling and willing to work with rats, mice.

Application:

Posted: June 18, 2021 (Remains active as of 9/1/22)