A postdoctoral research fellow position is available in the Department of Pharmaceutical Sciences at the University of Oklahoma Health Sciences Center, Oklahoma City. Dr. Joshi’s laboratory is seeking a highly motivated and proactive postdoctoral fellow to study role of nuclear receptor signaling in hepatic diseases. The successful candidate will utilize contemporary molecular, biochemical, and pharmacological approaches to decipher pathophysiological significance of Aryl hydrocarbon Receptor signaling in toxicology and metabolic diseases. This is an excellent opportunity to join a highly integrative, collaborative, and translational research group. For more information about our laboratory please visit: https://www.joshilaboratory.org/
Applicant should hold a Ph.D. in Biomedical Sciences. Preference will be given to the candidates with documented success in terms of first author publications and prior experience in molecular and cellular biology, microscopy, and mouse models. Highly motivated individuals who wish to develop careers in academia or pharmaceutical/toxicology industry are strongly encouraged to apply. Interested applicants should send their CV and a list of three references directly to aditya-joshi@ouhsc.edu.
Posted 2/5/2024
A postdoctoral research fellow position is available in the Department of Pharmaceutical Sciences at the University of Oklahoma Health Sciences Center, College of Pharmacy, Oklahoma City. Dr. S. Awasthi’s laboratory is seeking a highly motivated and enthusiastic postdoctoral research fellow to study the immunobiology of Toll-like receptors, pulmonary surfactant, and lung immune and epithelial cells. In this position, the postdoctoral researcher will help elucidate potential mechanism(s) involved in host cell immunomodulation. Multi-disciplinary approaches are utilized in Dr. S. Awasthi’s research projects including structural biology, biophysical, molecular, cellular, microbiological, biochemical, and immunological methods. The position will remain open until filled.
Qualifications: Applicants should possess a Ph.D. degree in Microbiology/Immunology/Biochemistry, or a related field in Biological Sciences with peer-reviewed publication(s). Experience with molecular and cell biology methods and mouse models is preferred. Competitive candidates are expected to have excellent oral and written communication skills and to be organized.
Interested applicants should send their CV and a list of three references to Shanjana-Awasthi@ouhsc.edu by e-mail.
Posted 12/19/2023
The Department of Ophthalmology at the University of Oklahoma Health Sciences Center is currently offering two postdoctoral fellow positions in vision research. These positions are funded by an NIH/NEI research grant, focusing on understanding the cellular and molecular mechanisms of photoreceptor degeneration and exploring therapeutic interventions. We are seeking Ph.D. graduates with a strong innovative focus, excellent communication skills, and a proven publication record. Preference will be given to individuals with a strong interest and experience in vision research.
To apply, please send a cover letter, curriculum vitae, and contact information for three references to Dr. Raju Rajala at the Department of Ophthalmology, University of Oklahoma Health Sciences Center, 608 Stanton L. Young Blvd., Oklahoma City, OK 73104. You can also reach Dr. Rajala by phone at (405) 271-8255, by fax at (405) 271-8128, or via email at raju-rajala@ouhsc.edu.
Multiple postdoctoral positions are available at the University of Oklahoma Health Sciences Center in Dr. Prabha Nagareddy’s lab at the Department of Medicine. The successful candidate will utilize molecular, genetic, immunological and pharmacological approaches to decipher the signaling pathways that regulate inflammation with a focus on myeloid cell production in different disease settings, including but not limited to diabetes, obesity, atherosclerosis, myocardial ischemia, etc.
Candidates must be able to design and perform experiments independently with appropriate but minimal supervision. Prior experience in flow cytometry including sorting and data analysis, mouse genetics, animal handling, bioinformatics, confocal microscopy and surgical techniques would be a distinct advantage. Highly motivated individuals who wish to develop careers in academia are encouraged to apply. Preference will be given to candidates with documented success in research, such as first author publications and aspirations for an independent scientific career. Please provide your CV, letter of specific research interests, and contact information for 3 references by email to Prabhakara-nagareddy@ouhsc.edu.
Postdoctoral Position in Bone Regeneration and Diabetic and Polycystic Kidney Diseases
A postdoctoral position is available at the University of Oklahoma Health Sciences Center in Dr. Mary Beth Humphrey’s lab to study molecular mechanisms of mesenchymal stem cell regulation and the gut microbiome on bone regeneration. Additional studies include the role of TREM2+ macrophages in kidney diseases.
Candidate should have a Ph.D. ideally with experience in bone biology, immunology, molecular biology, cell biology, or biochemistry. Experience with mammalian cell culture, recombinant DNA technology, cellular signaling and mouse models are preferred. Candidate must be able to plan and perform experiments in an independent manner with appropriate supervision, have excellent communication skills and strong interpersonal skills. Candidate will also be responsible for writing papers, protocols and lab reports associated with this project. Highly motivated individuals who wish to develop careers as independent scientists are encouraged to apply. Preference will be given to candidates with documented success in research, such as recent first author publications and aspirations for an independent scientific career. Please provide your CV, letter of interest, and contact information for 3 references, including current employer by email.
Contact via e-mail to marybeth-humphrey@ouhsc.edu.
Job Description---
A postdoctoral fellowship is available in the Pediatric Cardiovascular Research Laboratory of Dr. Harold M. Burkhart, Director of the Pediatric Cardiovascular Surgical program at Oklahoma Children’s Hospital and the University of Oklahoma Health Sciences Center (OUHSC). This is a multidisciplinary laboratory consisting of collaboration with Dr. Arshid Mir (Director of Pediatric Cardiology) and Dr. Chung-Hao Lee (School of Aerospace and Mechanical Engineering). We are seeking a highly motivated and independent postdoctoral fellow, with expertise in image-based cardiovascular computational modeling for congenital heart conditions. Dr. Burkhart’s research projects provide opportunities to have major, positive impacts on patients born with congenital heart conditions, such as hypoplastic left heart syndrome (HLHS) and atrioventricular canal defect, by developing patient-specific surgical planning strategies using state-of-the-art computational technologies. The lab also has previously funded projects focusing on stem cell therapy for HLHS, biomechanical and microstructural characterizations of tricuspid heart valve tissue, and in-silico biomechanical modeling for the cardiac valvular systems.
This is an excellent opportunity to join a highly integrative, translational and productive research group, with high-impact papers in top-tier journals including the Annals of Thoracic Surgery, the Journal of Thoracic and Cardiovascular Surgery, Computer Methods in Applied Mechanics and Engineering, Acta Biomaterialia, and Annals of Biomedical Engineering. The ideal candidate will be reliable, personable, highly motivated, and have demonstrated the ability to work independently. The candidate should be open to explore new opportunities and disciplines. The candidate is also expected to assist in writing grant proposals and will be highly encouraged to submit fellowship applications (both intramural and extramural) in order to help career development.
Other responsibilities will include communicating results to the scientific community through publications and presentations, and supervising graduate students, clinical residents, and laboratory technicians. Weekly attendance and presentation of data at lab meetings is expected. Presentation of results for submission of manuscripts to clinical and/or internationally recognized journals is expected for this position.
Job Requirements---
Our ideal candidate will have:
- A Ph.D. in the field of bioengineering, mechanical engineering, chemical engineering, or similar field
- Prior research experience should include bio-solid/bio-fluid computational modeling and image-based reconstruction of 3D geometry of pediatric cardiovascular systems
- Minimum of 2-3 year(s) experience with finite element analysis
- Experience with Python and/or other programming languages
- Experience with manuscript writing, statistical analysis, and preparation of figures for data/results is required
- Experience with virtual reality, 3D printing, and other techniques for visualizing pediatric hearts and heart valves is a benefit, but not required
- Experience with the scientific process of research study design, IRB approval is preferred
- A strong communication skill
- High level of initiative and technical proficiency and ability to collaborate within a highly interdisciplinary group
- Good record keeping skills and follow safety procedures and maintain a safe work environment
Salary & Benefits:
The position is full-time for one year with the option to extend dependent on the postdoctoral fellow’s performance and available funding. Salary will be based on the NIH stipend scale and will be commensurate with skills and experience. The University of Oklahoma Health Sciences Center (OUHSC) offers postdocs most employee benefits.
Application Instructions:
Applications should submit a CV (with contact information of a minimum of three [3] professional work references) and cover letter in electronic format (only) to Dr. Harold Burkhart, Director of the Pediatric Cardiovascular Surgical program at OUHSC at: harold-burkhart@ouhsc.edu
Questions about the position may be directed to Dr. Harold M. Burkhart harold-burkhart@ouhsc.edu or Dr. Chung-Hao Lee ch.lee@ou.edu
Equal Employment Opportunity Statement: The University of Oklahoma, in compliance with all applicable federal and state laws and regulations, does not discriminate on the basis of race, color, national origin, sex, sexual orientation, genetic information, gender identity, gender expression, age, religion, disability, political beliefs, or status as a veteran in any of its policies, practices, or procedures. This includes, but is not limited to, admissions, employment, financial aid, housing, services in educational programs or activities, and health care services that the University operates or provides.
Hiring contingent upon a Background Check? – Yes
Special Indications: None
Posted: 05/08/23 - Still Active 8/10/2023
12 month termed position; renewable contingent on funding
Job description
Biochemistry lab at The University of Oklahoma Health Sciences Center looking for a postdoctoral researcher. The group studies the relationship between brain metabolism and function, with particular emphasis on neuronal bioenergetics in the context of aging and cognitive decline. There will be opportunities to participate in several collaborative efforts aimed at understanding the metabolism of different cell types during aging or diseased states.
The ideal candidate must be a well-organized and independent scientist with experience in physiology/pharmacology, biochemistry, molecular biology (e.g. plasmids, viral expression vectors, and subcloning), and a strong background in fluorescence microscopy and/or electrophysiology. Hands-on experience related to laboratory animal work is preferred, as well as good record keeping and general laboratory practices including sterile technique. Tissue culture experience is also desired. The selected candidate is expected to maintain respectful and productive interactions with other lab members and collaborators.
Proposed/Current Job Responsibilities % of time spent on each
Mouse surgery (stereotactic injection of viral vectors) 15%
Molecular biology procedures / subcloning 20%
Microscopy/electrophysiology 50%
Lab management (ordering, organization) 10%
Tissue culture (cell line maintenance and transfection) 5%
TOTAL 100%
* The percentages of time spent in each activity may vary depending on the laboratory needs.
Basic qualifications
PhD degree or equivalent in Biochemistry, Physiology, Neuroscience or any other related discipline
Additional qualifications
Detailed guidance and training will be provided for each of the specific procedures used. All of the work requires focus and attention to detail and creative problem solving. Training and supervision of junior lab members is also expected.
Please submit a cover letter/email (letter of interest), a current CV and contact information for three references to Dr. Diaz Garcia (CarlosManlio-DiazGarcia@ouhsc.edu).
Posted: 04/27/23 - Still Active 8/10/23
The Post-Doctoral Fellow will develop and synthesize small molecule dyes, peptide-based contrast agents, or nanomaterials for cancer imaging and drug delivery applications. The Post-Doctoral Fellow will be responsible for synthesis, development, and evaluation of small molecule dyes (organic synthesis), peptide-based contrast agents, and/or nanomaterials (polymer and silica nanoparticles) to target the tumor microenvironment (breast, pancreatic, ovarian, and colon tumors).
The Post-Doctoral Fellow will work with existing laboratory members in the development small molecule dyes, peptide-based contrast agents, and/or nanoparticles for drug delivery with applications in cancer and inflammation. The Post Doc Fellow will work within our multi-disciplinary team to evaluate contrast agent specificity, toxicity, drug/dye release from nanoparticles, or efficacy using both in vitro and in vivo experimentation in murine, swine, and human of solid tumors. The Post Doc will have the opportunity to learn about writing and submitting their own independent federal grants (USA). Other responsibilities will include communicating results to the scientific community through publications and presentations, and supervising graduate students, clinical residents, and laboratory technicians. Weekly attendance and presentation of data at lab meeting is expected. Presentation of results for submission of manuscripts to international journals is expected for this position.
This position is funded by NIH grants.
Our ideal candidate will have:
- A Ph.D. in the field of chemistry, bioengineering, materials science, chemical engineering, biochemistry, biology or similar field;
- Prior research experience should include: organic chemistry, polymer chemistry, nanomaterials, or peptides-based agents
- Experience with standard characterization techniques required;
- Experience with manuscript writing, preparation of figures is required;
- Experience small animals (mice) is a benefit, but not required;
- Broad knowledge and experience in contrast agents and various imaging modalities is a strength;
- Must show technical proficiency and have the ability to collaborate within a multi-disciplinary group;
- Must have good record keeping skills;
- Must follow safety procedures and maintain a safe work environment;
- Strong interpersonal skills and the ability to contribute in a multidisciplinary team setting are mandatory.
Keywords: chemistry, organic chemistry, polymer chemistry, nanomaterials, nanoparticles, material science, contrast agent, imaging
The position is full-time for one year with the option to extend dependent on Post Doc performance and available funding. This project builds upon the work of Dr. Lacey McNally, an NIH funded investigator for the last 14 years. Salary will be based on experience and will use the NIH scale.
Interested candidates must apply online at https://jobs.ou.edu, job number 230418.
“The University of Oklahoma is an Equal Opportunity Institution. For more information go to www.ou.edu/eoo.”
Posted 3/8/2023 - Still Active 8/10/2023
A postdoctoral fellowship is available in the laboratory of Dr. Jacob E (Jed) Friedman, new Director of the Harold Hamm Diabetes Center at the University of Oklahoma Health Sciences Center. A major leadership gift of $34 million has allowed for the expansion of laboratories and Endowed Chairs for research on developmental origins of disease (DoHAD). We are seeking highly motivated and independent postdoctoral fellows, with expertise in nutrition and the molecular or clinical aspects of obesity, diabetes or its complications, specifically in the liver, adipose biology, or innate immune system. Dr. Friedman’s research projects provide opportunities to have major, positive impacts on human medicine by investigating how maternal obesity impacts the development of establishment of the innate immune system (bone and liver) and development of obesity and non-alcoholic fatty liver disease in Mouse, Monkey and Man. The lab also has funded projects focusing on nutrition and microbiome development and biomarkers of disease in humans and mouse models.
Expertise in assessment of the effects of nutrition on the development of adipose, liver, immunity, or microbiome is desired. Responsibilities will include working with mice, routine cell culture, protein and RNA isolation from cells and tissue, Western blotting, and tools for investigating epigenetics or cell transcriptomics in bone-marrow and liver-derived cells. The ideal candidate will be reliable, personable, highly motivated, and have demonstrated the ability to work independently. This is an excellent opportunity to join a highly integrative, translational and productive research group, with high impact papers in top journals including PNAS, JCI, Nature Communications, and Cell Reports.
https://medicine.ouhsc.edu/Academic-Departments/Physiology/Faculty/jacob-e-jed-friedman-phd
Dr. Friedman’s lab has state-of-the-art equipment including a Cytation 5 multi-mode imager, a Jess Simple Western system, and a QuantStudio 6 real-time PCR machine. Campus shared resources and cores include: Tissue Banking and Pathology; Biostatistics and Research Design; Mass Spectrometry / Proteomics; DNA Sequencing / Genomics; Flow Cytometry / Imaging; Diabetic Phenotyping; Germ-Free Facility; Non-Human Primates, and Mobile Health (mHealth) Technology Network (NCTN), with robust pilot funding and training grants in diabetes, cancer, gerosciences, and developmental immunology.
Prerequisites:
- Graduation from an accredited college or university with a PhD in nutrition, physiology, immunology, molecular biology, biochemistry, cell biology, or closely related fields
- Minimum of 2-3 year(s) experience in working with in vivo models relevant to obesity.
- Excellent communication skills
- Proven ability to work independently within a research lab.
- Demonstrated proficiency in computer software (Microsoft Office, SAS), standard laboratory equipment operation, and research technical skills
Salary & Benefits:
Salary will be based on the NIH stipend scale and will be commensurate with skills and experience. The University of Oklahoma Health Sciences Center offers postdocs most employee benefits.
Applicant Instructions
- Applicants may apply directly to Dr. Jacob Friedman, Director Harold Hamm Diabetes Center at: jed-friedman@ouhsc.edu
- Required application materials:
- Cover letter
- Resume/Curriculum Vitae
- Contact information for a minimum of [3] professional work references
The University of Oklahoma medical campus is committed to providing a safe and productive learning and living community. To achieve that goal, we conduct background investigations for all final applicants being considered for employment. Background investigations include a criminal history record check, and when appropriate, a financial and/or motor vehicle history.
The Immigration Reform and Control Act requires that verification of employment eligibility be documented for all new employees by the end of the third day of work. The University of Oklahoma strongly supports the principle of diversity. The University of Oklahoma is an Equal Opportunity Institution. Protected veterans and individuals with disabilities are encouraged to apply.
Please be advised that the University does check references as part of the employment process, and selection committee members may choose to contact work references during the search process other than those listed in your application.
The University of Oklahoma is an Affirmative Action/Equal Opportunity Employer http://www.ou.edu/eoo/ . Protected veterans and individuals with disabilities are encouraged to apply.
Posted 12/7/2022 - Still Active 8/10/2023
Postdoctoral Position in Radiation Oncology
Position Highlights
The laboratory of Dr. Dinesh Thotala at the at Oklahoma University Health Sciences Center is seeking a highly motivated Postdoctoral Research Fellow with a passion for cancer research and a strong background in immunology. The position offers a competitive salary based on the NIH pay lines.
Projects:
The candidate will investigate the mechanism behind radiation-induced immune suppression and the role of myeloid-derived suppressor cells in tumor immunity. Our laboratory specializes in exploring the cellular and molecular mechanisms that regulate T cell development, differentiation, activation, and effector function.
Responsibilities
The successful candidate will have the following responsibilities:
- Independently drive projects and develop innovative research ideas.
- Design and execute experiments using animal models, as well as experimental techniques in immunology, cell biology, and molecular biology.
- Collaborate effectively with diverse team members, including students, technicians, residents, and fellow postdoctoral researchers.
- Read and stay updated with recent publications and write manuscripts and fellowship applications.
- Present their research at national and international meetings.
Eligibility and requirements:
- A recent Ph.D. graduate in Immunology or a related discipline
- Demonstrated excellence in scholarly publications.
- Hands-on experience with animal models and experimental techniques pertinent to cellular immunology and molecular biology.
- Excellent command of the English language.
Preference:
Proficient in hands-on application of flow cytometry. Skilled in utilizing advanced molecular biology or biochemical techniques. Knowledge about single-cell RNA sequencing, CRISPR-Cas9 technology, genomics, and proteomics would be a plus.
Application Instructions:
To submit your application, kindly send an email to dinesh-thotala@ouhsc.edu including a cover letter delineating your research interests and demonstrating their compatibility with the laboratory's research objectives. Attach your Curriculum Vitae (CV) and provide contact details for at least two references.
Posted 4/15/2024
A postdoctoral position is available at the University of Oklahoma Health Sciences Center in Dr. Mary Beth Humphrey’s lab to study molecular mechanisms of mesenchymal stem cell regulation and the role of vagal nerve stimulation in prevent pain and joint destruction in mouse models of osteoarthritis.
Candidate should have a Ph.D. with experience in bone biology, immunology, molecular biology, cell biology, or biochemistry. Experience with mammalian cell culture, recombinant DNA technology, cellular signaling and mouse models of bone disease are preferred. Candidate must be able to plan and perform experiments in an independent manner with appropriate supervision, have excellent communication skills and strong interpersonal skills. Candidate will also be responsible for writing papers, protocols and lab reports associated with this project. Highly motivated individuals who wish to develop careers as independent scientists are encouraged to apply. Preference will be given to candidates with documented success in research, such as recent first author publications and aspirations for an independent scientific career. Please provide your CV, letter of interest, and contact information for 3 references, including current employer by email.
Contact via e-mail to marybeth-humphrey@ouhsc.edu.
Posted 9/28/22
A postdoctoral position at the Stephenson Cancer Center, University of Oklahoma Health Sciences Center (OUHSC) in Oklahoma City, Oklahoma, is immediately available to study chronic lymphocytic leukemia (CLL) biology and signaling involving crosstalk of the malignant cells with the CLL tumor microenvironment.
A highly motivated scientist with a fresh PhD is encouraged to apply. Candidates with experience in cancer biology, molecular biology, and animal models (xenograft as well as transgenic) are preferred. The candidate should have first-hand experience in routine laboratory techniques including but not limited to cell culture, western blots, immunoprecipitation, apoptosis assays, confocal microscopy, PCR/qRT-PCR and other related biochemical assays. Experience in flow cytometry will be an added qualification.
To apply, please send a cover letter stating your research interests and experience along with a curriculum vitae and three references to asish-ghosh@ouhsc.edu.
The Stephenson Cancer Center is an NCI-designated cancer center with interacting teams of scientists supported by an array of core facilities and located on a large OUHSC research campus. OUHSC is one of only four comprehensive academic health centers in the nation with seven health professional schools, providing a broad base of expertise for comprehensive clinical and basic science research, interdisciplinary interaction, and career development. Oklahoma City is a large metropolis with western charm, easy local transportation, vibrant downtown, and excellent suburbs.
The University of Oklahoma Health Sciences Center is an Equal Opportunity/Affirmative Action employer that is strongly and actively committed to diversity within its community. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, political beliefs, national origin, age (40 or older), sex (see: Sexual Misconduct, Discrimination policy) sexual orientation, genetic information, gender identity, gender expression, disability, or veteran status.
Posted: 7/6/22
A lab in University of Oklahoma Health Sciences Center (OUHSC) has an open position for a postdoctoral fellowship in cardiovascular drug development. Applicants with a strong background in cardiovascular research, including rodent model development, cell culture, advanced biochemical techniques, HPLC, etc. are especially encouraged. The successful candidate will be part of a dynamic lab with synergistic skills and experiences and will be given the opportunity to develop new projects that complement the overall directions of the lab. This is a mentored position where incumbents plan, design and conduct research experiments, manage research projects, prepare reports and papers for publication, presentation and future research. The fellow will actively contribute to grant writing and will be encouraged to write applications for independent fellowships. An ideal candidate will have Ph.D. in a biological science, chemistry, or other relevant area, or M.D., or equivalent. History of work in myocardial infarction and/or stroke mouse models preferred. Publication of at least 2-3 peer-reviewed articles is expected. Experience planning and effectively executing animal projects and maintaining animal colonies, surgical techniques, Western blotting, RT-PCR, Flow cytometry and other advanced molecular techniques. Must have the ability to multitask and work both independently and as a member of an interdisciplinary team with attention to detail.
Benchmark Expectations
- · Conduct scientific research.
- · Manage research projects and maintain documentation.
- · Present scientific information both formally and informally.
- · Prepare papers for publication and contribute to grant writing.
- · Perform lab management responsibilities as assigned.
- · Work collaboratively and collegially as part of the team while developing skills needed as an independent scientist.
- · Have experience and/or exposure to cardiovascular or a closely related field.
To apply, please send your current cv and a list of three references (email and phone number) to vawasthi@ouhsc.edu.
Posted 10/04/2021 - Still Active 8/10/2023
A postdoctoral position is available immediately in the Department of Biochemistry and Molecular Biology and the Center for Geroscience and Healthy Brain Aging at the University of Oklahoma Health Sciences Center. The applicant will work on mechanisms of pathogenesis of Alzheimer’s disease (AD) and related dementias using rodent models, with a specific focus on the role of mechanisms of aging, pathogenic tau, and cerebrovascular pathways of AD. For more information please see the laboratory’s website https://www.galvanlab.org.
The successful candidate should hold a Ph.D. in neuroscience, biochemistry, genetics, cellular or molecular biology, physiology, or other related fields and have a record of creativity and strong scientific productivity. Working experience on mouse models, assessment of brain vascular function, optical imaging, primary neuron cell culture, molecular biology and mouse genetics, and a background in neuroscience and brain vascular biology are strongly preferred, but not exclusively required. Please provide a curriculum vitae, a brief summary of research experience and goals, and the names and contact information of three references to Dr. Veronica Galvan (galvanv@uthscsa.edu) or to Dr. William Sonntag (william-sonntag@ouhsc.edu) on behalf of Dr. Veronica Galvan.
Posted: June 23, 2021