Available Postdoctoral Positions at OUHSC

Below are some of the postdoctoral positions available at OUHSC. Please note that this list is NOT comprehensive. If you do not see a position in your area of interest, you should directly contact OUHSC faculty who are working in your research area(s) to inquire about possible positions.

Please email Graduate College to add a new Postdoctoral Positions.

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Advertisement for a Postdoctoral Position:

A postdoctoral position at the Stephenson Cancer Center, University of Oklahoma Health Sciences Center (OUHSC) in Oklahoma City, Oklahoma, is immediately available to study chronic lymphocytic leukemia (CLL) biology and signaling involving crosstalk of the malignant cells with the CLL tumor microenvironment.

A highly motivated scientist with a fresh PhD is encouraged to apply. Candidates with experience in cancer biology, molecular biology, and animal models (xenograft as well as transgenic) are preferred. The candidate should have first-hand experience in routine laboratory techniques including but not limited to cell culture, western blots, immunoprecipitation, confocal microscopy, apoptosis assay, PCR/qRT-PCR and other related biochemical assays. Experience in flow cytometry will be an added qualification.

To apply, please send a cover letter stating your research interests and experience along with a curriculum vitae and three references to asish-ghosh@ouhsc.edu.

The Stephenson Cancer Center is an NCI-designated cancer center with interacting teams of scientists supported by an array of core facilities and located on a large OUHSC research campus. OUHSC is one of only four comprehensive academic health centers in the nation with seven health professional schools, providing a broad base of expertise for comprehensive clinical and basic science research, interdisciplinary interaction, and career development. Oklahoma City is a large metropolis with western charm, easy local transportation, vibrant downtown, and excellent suburbs.

The University of Oklahoma is an EO/AA Institution http://www.ou.edu/eoo/. Individuals with disabilities and protected veterans are encouraged to apply.

Posted: December 2, 2019


Stephenson Cancer Center

Several post-doctoral positions for immediate recruitment in the area of Nanomedicine, Immunotherapy, Cancer Gene Therapy, and Exosomes for Lung Cancer is available at the NCI-Designated Stephenson Cancer Center, University of Oklahoma Health Sciences Center (OUHSC) in Oklahoma City, Oklahoma. For all of the positions, highly motivated individuals with PhD., MD., or MD/PhD degree with good communication and writing skills in English are encouraged to apply.

First position is open to study the host-immune-response towards a RNA-binding protein in cancer. Candidate for this position should have strong experience in cancer immunology especially in the area of T- and NK cell biology. Knowledge of CAR-T cells is a plus. Studies will involve in vitro and in vivo studies and prior knowledge and expertise in the use of appropriate techniques and animal models is essential. Publications in relevant areas in peer-reviewed journals is required.

Second position is open to study the biogenesis and role of cancer exosomes in resistance to chemotherapy and immunotherapy. Candidates with prior experience in exosome and extracellular vesicle (EV) biology, biogenesis, and/or therapy is essential. Study will focus on investigating how exosomes and EVs negate cancer therapeutics and contribute to therapy failure. Studies will involve pre-clinical and clinical studies and handling of cancer patient samples (blood, urine, tissues, etc.) is expected. Publications in relevant areas in peer-reviewed journals is required.

Third position is open in the area of cancer nanomedicine and drug delivery. Individuals with expertise in synthesis of nanoparticles (lipid, polymer-, metal-based) for tumor- targeted drug (chemotherapy, plasmid DNA, siRNA, miRNA, imaging agents, etc.) delivery are eligible to apply. Experience in animal models (xenograft, PDX), nanoparticle synthesis, identifying new tumor targets for drug delivery, etc. is essential. Publications in relevant areas in peer-reviewed journals is required.

Fourth position is open to study interleukin (IL)-24 in cancer and immunity. Individuals with expertise in molecular biology, gene cloning, CRISPR/Cas 9, apoptosis, western blotting, animal tumor models, flow-cytometry, organoids, etc., is essential. Publications in relevant area of research in peer-reviewed journals is required.

To apply, please email a cover letter stating your research interests and experience along with curriculum vitae and three references to:

Dr. Rajagopal Ramesh, Professor & Jim and Christy Everest Endowed Chair in Cancer Developmental Therapeutics, Department of Pathology,

 

University of Oklahoma Health Sciences Center 975 N.E., 10th Street, Oklahoma City, OK 73104 Phone: (405) 271-6101

 

Email: rajagopal-ramesh@ouhsc.edu

 

The Stephenson Cancer Center is an NCI-designated cancer center with interacting teams of scientists supported by an array of core facilities and located on a large OUHSC research campus. OUHSC is one of only four comprehensive academic health centers in the nation with seven health professional schools, providing a broad base of expertise for comprehensive clinical and basic science research, interdisciplinary interaction, and career development. Oklahoma City is a large metropolis with western charm, easy local transportation, vibrant downtown, and excellent suburbs.

 

The University of Oklahoma is an EO/AA Institution http://www.ou.edu/eoo/.

Posted: October 21, 2019

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A postdoctoral position at the Stephenson Cancer Center, University of Oklahoma Health Sciences Center (OUHSC) in Oklahoma City, Oklahoma, is immediately available to study colon and liver cancers in the context of inflammation, immune regulation and gut microbiome.

 A highly motivated scientist with PhD degree and some postdoctoral experience in the relevant areas is encouraged to apply. Candidates with experience in microbiome studies, cancer biology, molecular biology, tumor immunity, and animal models (xenograft as well as transgenic) are preferred.

 To apply, please send a cover letter stating your research interests and experience along with a curriculum vitae and three references to mark-huycke@ouhsc.edu. The Stephenson Cancer Center is an NCI-designated cancer center with interacting teams of scientists supported by an array of core facilities and located on a large OUHSC research campus. OUHSC is one of only four comprehensive academic health centers in the nation with seven health professional schools, providing a broad base of expertise for comprehensive clinical and basic science research, interdisciplinary interaction, and career development. Oklahoma City is a large metropolis with western charm, easy local transportation, vibrant downtown, and excellent suburbs.

 The University of Oklahoma is an EO/AA Institution http://www.ou.edu/eoo/. Individuals with disabilities and protected veterans are encouraged to apply.

Posted: October 17, 2019

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Position Title: Postdoctoral Research Fellow

Department: Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine at the University of Oklahoma Health Sciences Center (OUHSC).

Description: A Postdoctoral Research Fellow position is available in the laboratory of Dr. Matthew Walters, Ph.D. The major focus of the Walters laboratory is to understand the processes that regulate lung regeneration during health and in response to environmental insult (e.g. cigarette smoke). Using both in vitro and in vivo models, the Postdoctoral Research Fellow will work on projects related to studying the role of Notch signaling in regulating differentiation of human airway epithelial stem/progenitor cells in the context of cigarette smoking-induced lung disease, including chronic obstructive pulmonary disease (COPD).

Requirements: We are seeking a highly motivated, self-driven individual with a strong background in molecular biology and cell biology. Experience with cell culture, stem cell biology and/or mouse models is preferred. The successful candidate will hold a Ph.D., be well organized, be a self-starter and a team player, and have excellent written and verbal communication skills.

Additional Information (including how to apply): Interested candidates should send a letter that describes your scientific interest and research experience, together with your CV (including a list of all publications) and the names of three references to Dr. Matthew Walters (Matthew-S-Walters@ouhsc.edu). For more information about our research please visit our website (https://www.oumedicine.com/department-of-internal-medicine/department-sections/pulmonary-critical-care-sleep-medicine/research/walters).

Contact Information:

Matthew Walters, PhD  | Assistant Professor of Medicine |Pulmonary, Critical Care and Sleep Medicine |Department of Medicine

University of Oklahoma Health Sciences Center, 800 N. Research Parkway, Building 800, 4th Floor, Rm 410. Oklahoma City, OK 73104, Office: 405-271-3803 , Lab: 405-271-8000 ext 57387 or 57357

Application Deadline: Position open until filled.

Posted: September 6, 2019

 


Postdoctoral Position in Ocular Immunology

 An NIH-funded position is available for a Postdoctoral Fellow in the Department of Ophthalmology at the University of Oklahoma Health Sciences Center.

 Candidates with experience in immunology, molecular biology, physiology, and/or cell biology who are highly motivated and enthusiastic are encouraged to apply. Experience with mice, cell culture, and writing papers is required. He or she must be able to multi-task, work in a team setting as well as independently, and have excellent oral and written communication skills. Proficiency with ocular mouse models and flow cytometry is preferred.

 Dr. Darren Lee’s lab is interested in autoimmune uveitis and the mechanisms that promote resolution.

 Interested individuals should send an updated CV and contact information for three references to Darren-lee@ouhsc.edu

Posted: September 6, 2019 


Postdoctoral position

 

One postdoctoral research fellow position is available in the Department of Pharmaceutical Sciences at the University of Oklahoma Health Sciences Center, College of Pharmacy, Oklahoma City. Dr. S. Awasthi’s research group is seeking a highly motivated and enthusiastic postdoctoral research fellow to study the immunomodulation and biological activity of Toll-like receptor 4-interacting SPA4 peptide. In this position, the postdoctoral researcher will help elucidate potential mechanism(s) involved in host cell immunomodulation. Multi-disciplinary approaches are utilized in Dr. S. Awasthi’s research program including structural, biophysical, molecular, cellular, microbiological, biochemical and immunological studies. The position will remain open until filled.

 

Qualifications: Applicants should possess a Ph.D. degree in Microbiology/Immunology/Biochemistry, or a related field in Biological Sciences with peer-reviewed publication(s). Experience with molecular and cell biology methods and mouse models is required. Competitive candidates are expected to have excellent oral and written communication skills, to be organized, and to work easily with others in the laboratory as a team player.

Interested applicants should send their CV and a list of three references to Shanjana-Awasthi@ouhsc.edu by e-mail.

Posted: September 6, 2019


Position Title: Postdoctoral Research Fellow

A postdoctoral position is available in the Stephenson Cancer Center at the University of Oklahoma Health Sciences Center (OUHSC) to study protein tyrosine kinases and phosphatases in cancer biology and therapy. Areas of research include roles and mechanisms of protein tyrosine kinases and phosphatases in oncogenesis, responses to therapy, cancer genomics, immune-oncology, and drug discovery.


Highly motivated individuals with a recent doctoral degree and a solid background and skills in molecular cell biology, biochemistry, pharmacology, immunology, or animal models are encouraged to apply. The appointee will be expected to participate in experimental design, perform original experiments, collect and evaluate data; develop new research techniques and procedures; publish original research findings; and participate in research meetings. The ideal candidate should be able to take a lead role on a project and report to the PI.


To apply, please send a cover letter stating your research interests and experience along with a curriculum vitae and the names of three references to Dr. Jie Wu at jie-wu@ouhsc.edu.

Posted: September 6, 2019


Post-Doctoral Position in (protein chemistry, bacterial toxin biology)

 

A post-doctoral position is available immediately for a talented individual with a PhD in (topic of PHD) and significant experience in protein chemistry. The successful applicant will join a multidisciplinary research group at the University of Oklahoma Health Sciences Center with collaborators at Harvard University and the University of Melbourne, Australia.The initial direction of the project will entail studies to investigate the activation of pore-forming toxins produced by and involved in the pathogenesis of a wide variety of major bacterial pathogens. The successful candidate will also be involved in the study of a new class of related pore-forming proteins that are widespread in bacterial species that are important to human microbiome, but which are also widespread in the terrestrial environment. This project and position are funded by the National Institutes of Health (NIAID). Salary for the post-doctoral position will be commensurate with experience and the NIH post-doc salary scale. The University of Oklahoma is an Affirmative Action Equal Opportunity Employer and encourages individuals with disabilities and protected veterans to apply.

 

To Apply: Send applications by email in a single PDF. The application package will include a 1-2 page cover letter describing research interests and short- and long-term goals, an NIH-format bio-sketch, and the names and contact information of three referees. Applications should be sent directly to Dr. Rodney Tweten at rod-tweten@ouhsc.edu   

Posted: September 6, 2019 

 


Department of Medicine, Division of Endocrinology

4/16/2018

Research Positions available for NIH-funded projects:

The Wang lab at OUHSC Department of Medicine, Division of Endocrinology is seeking highly motivated postdoctoral researchers in the area of diabetes research. The positions can start immediately. The candidates will study the roles and mechanisms of several novel genes and chemicals we recently identified in pancreatic beta cell biology, insulin action, insulin resistance, and other aspects in the pathogenesis of diabetes. Molecular and cellular biology and biochemical techniques as well as transgenic/knockout mouse models will be utilized for these studies. A Ph.D. in Biochemistry, Molecular or Cell Biology, Pharmacology or related field is required. Strong expertise in molecular and cellular biology, protein biochemistry, or experience with mouse models of diabetes or of metabolic disorders is preferred.

Candidates must be self-driven, highly motivated and well organized, and have published first-author papers in internationally recognized journals. Must be able to multi-task and solve problems creatively, with the ability to work independently as well as cooperatively with a team. Excellent oral and written communication skills are required.  

Interested candidates should send a letter that describes your scientific interest and research experience, together with your CV, list of publications and the names of three references to Dr. Weidong Wang at weidong-wang@ouhsc.edu. Please also visit our website http://www.ouhsc.edu/endocrinology/faculty/Wang.asp for more information about our research.

Posted: March 21, 2019

 


Postdoctoral Position in Cardiovascular Immunology

 

A postdoctoral position is available at the University of Oklahoma Health Sciences Center in the lab of Dr. Stavros Stavrakis (co-mentored by Dr. Mary Beth Humphrey) to study molecular mechanisms by which vagal nerve stimulation improves heart failure with preserved ejection fraction (HFpEF). Studies include use of a high salt diet-induced model of HFpEF in rats. We will be immunophenotyping cardiac and splenic myeloid cells and T cells from this model and test for the functional role of these immune cell subsets during the development of HFpEF. Further studies will investigate the changes in these immune cells in response to vagal nerve stimulation in the model.

Candidate should have a Ph.D. with experience in immunology, molecular biology, cell biology, physiology, or biochemistry.  Experience with mammalian cell culture, recombinant DNA technology, cellular signaling and rodent models of disease are preferred.   Candidate must be able to plan and perform experiments in an independent manner with appropriate supervision, have excellent communication skills and strong interpersonal skills.  Candidate will also be responsible for writing papers, protocols and lab reports associated with this project. Highly motivated individuals who wish to develop careers as independent scientists are encouraged to apply.  Preference will be given to candidates with documented success in research, such as recent first author publications and aspirations for an independent scientific career.  Please provide a CV and contact information for 3 references, including current employer by email.

Contact via e-mail to Stavros-stavrakis@ouhsc.edu

Posted: September 6, 2019


Post-Doctoral Fellow/Trainee in Developmental Origins of Health and Disease
Position Information: 
Post-doctoral fellowships are available in the laboratory of Dr. Jacob E (Jed) Friedman, new Director of the Harold Hamm Diabetes Center at the University of Oklahoma Health Sciences Center. A major leadership gift of $34 million has allowed for the expansion of laboratories and Endowed Chairs for research on developmental origins of disease (DoHAD).We are seeking highly motivated and independent postdoctoral fellows, with expertise in the molecular or clinical aspects of obesity and maternal and neonatal physiology. The research projects provide opportunities to have major, positive impacts on human medicine by investigating how maternal obesity impacts the development of infant innate immunity and how breast milk and the microbiome contribute to establishment of adiposity and abnormal development of obesity and non-alcoholic fatty liver disease  in Mouse, Monkey and Man (Nature Communications 2018 Diabetes 2018; Microbial Cell 2018; Molecular Metabolism 2018; Nature Reviews-GI and Hepatology 2016 ). https://hammdiabetescenter.org/About-Us/Meet-the-Director

 

Expertise in assessment of the effects of maternal obesity on the development of metabolic systems is desired.Responsibilities will include working with germ-free mice, human breast milk and infant blood/stool relevant to maternal obesity/diabetes, routine cell culture, protein and RNA isolation from cells and tissue, Western blotting, and ATAC-seq tools for investigating epigenetics in bone-marrow and liver macrophages. The ideal candidate will be reliable, personable, highly motivated, and have demonstrated the ability to work independently. This is an excellent opportunity to join a highly integrative, translational and productive research group.  https://hammdiabetescenter.org/Research/Programs

 

Dr. Friedman’s lab has state-of-the-art equipment including a Cytation 5 multi-mode imager, a Jess Simple Western system, and a QuantStudio 6 real-time PCR machine. Campus shared resources and cores include: Tissue Banking and Pathology; Biostatistics and Research Design; Mass Spectrometry / Proteomics; DNA Sequencing / Genomics; Flow Cytometry / Imaging; Diabetic Phenotyping; Germ-Free Facility; Non-Human Primates, and Mobile Health (mHealth) Technology Network (NCTN), with robust pilot funding and training grants in diabetes, cancer, gerosciences, and developmental immunology.

 

 

 

  • Graduation from an accredited college or university with a PhD in nutrition, physiology, immunology, molecular biology, biochemistry, cell biology, or closely related fields
  • Minimum of 2-3 year(s) experience in working with in vivo models relevant to obesity.
  • Excellent communication skills
  • Proven ability to work independently within a research lab.
  • Demonstrated proficiency in computer software (Microsoft Office, SAS), standard laboratory equipment operation, and research technical skills

 

Salary will be based on the NIH stipend scale and will be commensurate with skills and experience. The University of Oklahoma Health Sciences Center offers postdocs most employee benefits.  

 

Applicant Instructions

 

  • Applicants may apply directly to Dr. Jacob Friedman, Director Harold Hamm Diabetes Center at:  jed-friedman@ouhsc.edu
  • Applications received by Dec 31, 2019 will receive full consideration.
  • Required application materials:

 

    • Cover letter
    • Resume/Curriculum Vitae
    • Contact information for a minimum of [3] professional work references

 

The University of Oklahoma medical campus is committed to providing a safe and productive learning and living community.To achieve that goal, we conduct background investigations for all final applicants being considered for employment.Background investigations include a criminal history record check, and when appropriate, a financial and/or motor vehicle history.

 

The Immigration Reform and Control Act requires that verification of employment eligibility be documented for all new employees by the end of the third day of work. The University of Oklahoma strongly supports the principle of diversity.  The University of Oklahoma is an Equal Opportunity Institution. Protected veterans and individuals with disabilities are encouraged to apply.

 

Please be advised that the University does check references as part of the employment process, and selection committee members may choose to contact work references during the search process other than those listed in your application.

Posted: October 10, 2019


Position Title: Postdoctoral Research Fellow (Three Positions Available)

  • Department: Medicine, Surgery, and the Stephenson Cancer Center (SCC)
  • Description: Three post-doctoral fellow positions are open immediately in Dr. Min Li's lab in the Department of Medicine, Department of Surgery at The University of Oklahoma Health Sciences Center (OUHSC) and the Stephenson Cancer Center (SCC). Our projects include molecular mechanisms and translational research on pancreatic cancer, other GI cancers and brain tumor (PNAS 2007; Clin Can Res 2009, 2010; EMBO Mol Med 2013; Oncogene 2014, etc). 
  • Requirements: The successful candidates must be highly self-motivated with a strong background in molecular biology and cell biology. Experience with mouse models is preferred. Experience in pharmacology, or bioinformatics is also welcomed. The candidate will work with an established investigator (supported by multiple NIH/NCI R01 grants and private funding), and as well as a strong clinical team (including surgeons and gastroenterologists). The successful candidate will get a competitive stipend and have access to state-of the art facilities, both at the OUHSC and the Stephenson Cancer Center. 
  • Additional Information (including how to apply): Please submit your CV, a research summary, and names and addresses of three references via email to: Frieda-Hindman@ouhsc.edu

Application Deadline:  Position open until filled.

Posted: September 6, 2019


  

Advertisement for a Postdoctoral Fellowship in Human Performance

 

 

 

One, 2-year postdoctoral position is immediately available at the Center for Human Performance Measurement (Center) in the Department of Rehabilitation Sciences, University of Oklahoma Health Sciences Center (OUHSC) in Oklahoma City, Oklahoma, to develop translational skills in:1) advanced, comprehensive, integrated motion analysis; 2) research project management; 3) mentoring and teaching. The training program follows the practitioner-investigator model in that a postdoc fellow is provided with intensive training in the application of the scientific method within the context of clinical translational research.As part of this practitioner-investigator model, the program adheres to a philosophy of utilizing empirically-based methods of clinical translational research.For more details of the fellowship, please visit: https://alliedhealth.ouhsc.edu/Labs/Center-for-Human-Performance-Measurement.

 

Highly motivated clinician scientists with a recent PhD are encouraged to apply. Candidates with experience in orthopedic physical therapy are preferred. The most qualified candidate should be license-eligible in Physical Therapy in the State of Oklahoma and possess clinical expertise in orthopedics, biomechanics, and advanced knowledge in human anatomy and movement sciences.

 

Salary is $50,004 per year plus fringe as an exempt position.

 

The Center is a University re-charge facility that helps researchers study biomechanical aspects of human movement through kinematics, kinetics and muscle activation from a 3-dimensional perspective. This facility is the sole provider of such human performance measurement to the region. OUHSC is one of only four comprehensive academic health centers in the nation with seven health professional schools, providing a broad base of expertise for comprehensive clinical and basic science research, interdisciplinary interaction, and career development. Oklahoma City is a large metropolis with western charm, easy local transportation, vibrant downtown, and excellent suburbs.

 

 

 

To apply:

 

Please send a cover letter stating your research interests and experience along with a curriculum vitae and three references to: 

 

Carol P. Dionne, PT, DPT, PhD, MS, OCS, Cert MDT | Department of Rehabilitation Sciences 

1200 N. Stonewall Ave. Oklahoma City, Oklahoma 73117, 405-271-2131 ext 47115 - carol-dionne@ouhsc.edu .

 

Additional Information: The University of Oklahoma is an EO/AA Institution http://www.ou.edu/eoo/. This link to the Postdoc Handbook where applicants can find all of the policies and procedures covering postdoctoral fellows.  Application Deadline: Position open until filled.

Posted: October 10, 2019


 

Postdoctoral Fellowship in Tobacco Regulatory Science Research

 

The Oklahoma Tobacco Research Center (OTRC) of the Stephenson Cancer Center at the University of Oklahoma Health Sciences Center in Oklahoma City announces a post-doctoral fellowship opportunity (1-3 year appointments) for a fellow who aspires to become an independent academic researcher in the areas of tobacco regulatory science research, tobacco health communication, tobacco use/cessation, and/or health disparities and comorbidities research. The fellow will be encouraged to develop new research in related areas and will have the opportunity to be involved in ongoing NIH/FDA-funded clinical trials on tobacco use, as well as secondary analysis of completed NIH/FDA studies.

 

The fellow will work primarily with Dr. Amy Cohn and her team to conduct laboratory, experimental, and/or epidemiological research in areas relevant to tobacco regulatory science and tobacco prevention in at-risk and vulnerable populations, including youth, young adults, and smokers with mental health and substance use comorbidities. Dr. Cohn’s current NIH-funded research focuses on understanding young adult appeal for flavored tobacco products, including menthol cigarettes, as well as the co-use of tobacco with alcohol and marijuana. This research aims to inform FDA tobacco product regulation and policies, as well as identify targets for modification in prevention and intervention efforts. Dr. Cohn’s research uses a variety of methodological approaches, including ecological momentary assessment, secondary analysis of large population-based surveys, laboratory smoking topography studies, behavioral economic paradigms, and computer-based experimental tasks. Other ongoing research will develop and evaluate tobacco and marijuana use health risk messages, and improving smoking cessation programs for smokers with mental health and substance use comorbidities. The fellow will have access to training and research opportunities as part of the OU PRIME (Psychological Research on Information and Media Effects) Lab in the Center for Applied Social Research at the University of Oklahoma Gaylord College of Journalism and Mass Communication, and the Tobacco Treatment Research Program (TTRP) at OTRC. The OU Prime Lab is specifically designed to conduct cutting-edge research on how individuals cognitively and emotionally process media and health communication messages, including anti-tobacco messaging ( https://ou-primelab.oucreate.com/lab/. The TTRP offers free tobacco cessation counseling and pharmacotherapy to adults from campus and the community. For more information, please visit the OTRC website: ( http://otrc.stephensoncancercenter.org/home.aspx).

 

The fellow will be highly involved in manuscript preparation using data from completed and ongoing studies, as well as existing population-based datasets. Fellows will also take part in the formal OTRC training program, which includes coursework and seminars that provide training in grant writing and preparation, conducting laboratory research, tobacco-related research methods, and advanced statistical techniques.

 

Qualifications include a doctoral degree in social/behavioral sciences, public health, psychology, or other relevant area. Excellent writing and analytic skills required. Experience with tobacco research, experimental methods, and quantitative methods are preferred. Applicants with interest in health disparities (including co-occurring substance use), health communication, and/or tobacco product marketing (i.e., advertising, labeling, and/or packaging characteristics) encouraged to apply. Salary and benefits are excellent. In addition, fellows will have access to funds to conduct research, and attend external trainings and conferences.

 

Interested candidates should send a cover letter, curriculum vitae, statement of research interests, and 3 letters of reference to: Dr. Amy Cohn c/o Mr. Derek Matthesen at Derek-Matthesen@ouhsc.edu and include “Cohn” in the subject line.

Posted: September 9, 2019

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Postdoctoral Position in Molecular Parasitology

 

A postdoctoral or staff scientist position is available immediately for a talented individual with a Ph.D. in microbiology or related field and significant experience in one or more of the following areas: second messenger signaling, microbial motility, heterologous gene expression in yeast, CRISPR/Cas genome editing, and/or molecular parasitology. The successful applicant will join a new molecular parasitology laboratory that uses Toxoplasma gondii, a highly tractable apicomplexan parasite, to investigate how apicomplexans turn on motility to locate, enter, and exit host cells. Apicomplexans depend on cyclic GMP (cGMP) signaling to activate motility, yet it is unclear how this signal is generated. This NIH-funded project will explore how apicomplexans generate cGMP using an unusual class of hybrid P4-ATPase-guanylate cyclase enzymes. Applicants should have sufficient experience with cellular, genetic, and molecular biology techniques to play a leading role in achieving the project goals. Salary for the postdoctoral position will follow the NIH postdoc salary scale. Salary for recruitment at the staff scientist level will be commensurate with experience. The University of Oklahoma is an Affirmative Action Equal Opportunity Employer and encourages individuals with disabilities and protected veterans to apply.

 

To Apply: Send applications by email in a single PDF. The application package will include a 1-2 page cover letter describing research interests and short- and long-term goals, an NIH-format bio-sketch or C.V., and the names and contact information of three referees. Applications should be sent directly to Dr. Kevin M. Brown, kevin-brown@ouhsc.edu 

Posted: September 6, 2019  

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Postdoctoral Position in Cell Surface Receptor Structure and Function

 

An NIH-funded postdoctoral position in cell surface receptor structure and function is available in the Pioszak laboratory in the Department of Biochemistry and Molecular Biology at the University of Oklahoma Health Sciences Center in Oklahoma City.  Projects involve structure/function studies of clinically important human cell surface receptors.  The position will involve a variety of biochemical and pharmacological approaches as well as structural studies using X-ray crystallography and/or Cryo-EM.

 

Applicants should hold a recent Ph.D. in Biochemistry, Pharmacology, or related area.  Experience with molecular biology techniques, protein expression and purification, protein-ligand interaction methods, cell culture, pharmacological assays, and X-ray crystallography or Cryo-EM would be an advantage, but experience in all of these areas is not required.  Strong motivation and a strong work ethic are a must. Salary to be commensurate with qualifications/experience and the NIH postdoc salary scale.

 

To apply, please send a single pdf including cover letter, CV, and the names and contact information for 3 references to augen-pioszak@ouhsc.edu.

 

For more information on the Pioszak lab please consult our webpage:

 

https://basicsciences.ouhsc.edu/bmb/Faculty/bio_details/pioszak-augen-a-phd

 

The University of Oklahoma is an Affirmative Action/Equal Opportunity Employer.

Posted: September 6, 2019

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Job Posting Title: Postdoctoral Research Associate in Computational Biology and Bioinformatics and the Harold Hamm Diabetes Center

 

 

 

Position Description:

 

The Harold Hamm Diabetes Center (HHDC) at the University of Oklahoma (OU) invites applications for a postdoctoral research associate position in computational biology and bioinformatics. HHDC has an exceptional and expanding research program focusing on the early origins of diabetes and obesity in children. The candidate will be co-mentored by HHDC Member, Dr. Chongle Pan, and HHDC Director, Dr. Jacob E. Friedman. Dr. Pan is an Associate Professor in the School of Computer Science and the Department of Microbiology and Plant Biology in OU Norman. Dr. Friedman is a Professor of Physiology, Biochemistry & Molecular Biology, and Pediatrics & Medicine at OU Health Sciences Center.

 

They have formed an active ongoing collaboration and partnership for tools ranging from transcriptomics, metabolomics, epigenetics, to metagenomics of the microbiome.

 

https://hammdiabetescenter.org/About-Us/Meet-the-Director

 

http://www.ou.edu/coe/cs/people/pan

 

http://www.ou.edu/cas/mpbio/people/faculty/pan

 

The research will focus on the characterization of risk factors for diabetes in early childhood. The risk factors will include childhood microbiota dysbiosis, genetic predisposition, and maternal metabolism disorders. Key molecular determinants for these risk factors will be identified from multi-omics data, which will be used to develop testable hypotheses for follow-on molecular biology experiments and build computational models for predicting and understanding diabetes.

 

Job Responsibilities:

 

The candidate is responsible for analyzing and mining multi-omics data using computational techniques, such as machine learning, generalized linear mixed models, and biological network analysis. This may require development of new computer algorithms and/or construction of computational workflows on computer clusters. The types of multi-omics data will include longitudinal metagenomics sequencing data, genome-wide association (GWAS) data, proteomics data, and metabolomics data. The candidate is expected to publish their findings in peer-reviewed journals.

 

Qualifications:

 

 

 

Ph.D. in bioinformatics, computer science, or a related field.

 

Strong publication track record

 

Relevant prior research experience

 

Application Instructions:

 

Patricia-Parker@ouhsc.edu

 

cpan@ou.edu jed-friedman@ouhsc.edu

Posted: September 6, 2019

 

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Department: Department of Medicine, Division of Rheumatology, Immunology, and Allergy at the University of Oklahoma Health Sciences Center (OUHSC).

 

Description: A postdoctoral position is available in the laboratory of Dr. Matlock A Jeffries, MD. The major focus of Dr. Jeffries’s lab is understanding the ways in which environmental factors influence osteoarthritis (OA) risk by modulating epigenetic factors both locally within the joint and systemically, and whether epigenetic modifications might be used as biomarkers for human OA diagnosis and progression. Using both in vitro and in vivo models, the Postdoctoral Research Fellow will work on projects studying the epigenetic consequences of aging, obesity, and trauma to mouse OA development, as well as projects investigating the role of the microbiome on systemic inflammation in OA. The Jeffries laboratory also studies epigenetic editing, and there will be a possibility for the postdoctoral research fellow to work on in vitro epigenetic editing of OA-relevant tissues as well.

 

Requirements: We are seeking a highly motivated and driven individual with a background in epigenetics and/or microbiome analysis and OA, with good fundamental cell biology skills and a willingness to learn rodent microsurgical techniques as they apply to OA. Experience with cell culture, viral transduction, mouse models, and strong computing / data analysis skills are preferred. The successful candidate will hold an MD or PhD degree, be highly organized, independently capable, a team player, and have excellent communication skills.

 

Interested individuals should send an updated CV or NIH biosketch, a cover letter, and information for three references to Dr. Matlock Jeffries Matlock-Jeffries@ouhsc.edu 

Posted: September 6, 2019

 

 

 

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 Postdoctoral Research Fellow

 

 Department of Physiology and Ophthalmology, at the University of Oklahoma Health Sciences Center (OUHSC).

 

 A postdoctoral position is available in the Department of Physiology and Ophthalmology at the University of Oklahoma Health Sciences Center (OUHSC) to study Phosphoinositide Signaling and its effect on the Neuroprotection of the Retina as well as Retina/RPE Metabolism and Metabolic Reprogramming. Areas of research include Biochemistry, Molecular Biology, and Genetic Engineering.

 

 We are seeking a highly motivated, self-driven individuals with a strong background in molecular biology and cell biology. Preference will be given to candidates who have experience in cell signaling. The successful candidate will hold a Ph.D., be well organized, independent, a team player, and have excellent written and verbal communication skills.

 

Additional Information (including how to apply):  Interested candidates should send a letter that describes your scientific interest and research experience, together with your CV (including a list of all publications) and the names of three references who can assess your candidature to Dr. Raju Rajala ( raju-rajala@ouhsc.edu).

 

 

 

 Position open until filled. 

Posted: September 6, 2019